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Opioid Overdose Prevention Toolkit (Updated)

Facts for Community Members

1. When someone loses tolerance and then takes the opioid drug again, they can experience serious adverse effects, including overdose, even if they take an amount that caused them no problem in the past.

A. True

B. False


2. Which of the following is a strategy to prevent overdose deaths?

A. Encourage providers, persons of high risk, family members, and others to learn how to prevent and manage opioid overdose.

B. Ensure access to treatment for individuals who are misusing or addicted to opioids or who have other substance use disorders.

C. Ensure ready access to naloxone.

D. All of the above.


3. Naloxone is effective in treating overdoses of:

A. Benzodiazepines

B. Opioids

C. Barbiturates

D. All of the above


4. Naloxone does not have the potential for abuse.

A. True

B. False


Five Essential Steps for First Responders

5. Which of the following is a sign of an overdose?

A. Extreme sleepiness, inability to awaken verbally or upon sternal rub.

B. Breathing problems that can range from slow to shallow breathing in a patient that cannot be awakened.

C. Fingernails or lips turning blue / purple.

D. All of the above.


6. One telltale sign of a person in a critical medical state is:

A. The death rattle

B. A slow heartbeat

C. Pinpoint pupils

D. Slurred speech


7. The most rapid onset of action by naloxone is achieved by _____ administration, which is recommended in emergency situations.

A. Intranasal

B. Intramuscular

C. Intravenous

D. Subcutaneous


8. The goal of naloxone therapy should be complete arousal.

A. True

B. False


9. More than one dose of naloxone should never be given to someone who is overdosing.

A. True

B. False


10. Naloxone cannot be used in pregnant women.

A. True

B. False


11. All patients should be monitored for recurrence of signs and symptoms of opioid toxicity for at least _____ hours from the last dose of naloxone or discontinuation of the naloxone infusion.

A. 2

B. 4

C. 8

D. 12


12. All of the following should be done when responding to opioid overdose, except for:

A. Put the person into a cold bath or shower.

B. Support the person’s breathing by administering oxygen or performing rescue breathing.

C. Put the person in the “recovery position” on the side, if he or she is breathing independently.

D. Stay with the person and keep him / her warm.


Information for Prescribers

13. Which of the following patients is a candidate for a naloxone kit?

A. Taking high doses of opioids for long-term management of chronic malignant or non-malignant pain.

B. Receiving rotating opioid medication regimens.

C. Discharged from emergency medical care following opioid intoxication or poisoning.

D. All of the above.


14. Rapid opioid withdrawal in tolerant patients is not typically life-threatening.

A. True

B. False


15. Which of the following is the single most important intervention for opioid overdose?

A. Administering naloxone

B. Putting the person in the “recovery position”

C. Supporting respiration

D. Making the person vomit the drugs


Safety Advice for Patients & Family Members

16. Naloxone may cause all of the following, which may worsen if it is taken with alcohol or certain medicines, except for:

A. Seizures

B. Dizziness

C. Drowsiness

D. Fainting


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