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Quantum Units Education

Neuroscience and Novel Therapeutics for Mental Illness

Introduction

1. Cognitive deficits are the single best predictor of functional outcomes of schizophrenia.

A. True

B. False


Video Presentation: Translating Neural Circuits into Novel Therapeutics

2. If a patient with schizophrenia is asked to perform a working memory task, gamma synchrony in the prefrontal cortex, measured by EEG, is which of the following?

A. Higher than in normal controls.

B. Lower than in normal controls.

C. The same as in normal controls.

D. Can not be determined.


Video Presentation: What is the Relationship Between Fear/Safety, Anxiety, and Anxiety Disorders?

3. Which of the following symptoms exist when an anxiety disorder is present?

A. Fear and anxiety are greater than expected.

B. Fear and anxiety last beyond what is adaptive.

C. Fear and anxiety affect well being and function.

D. All of the above.


4. It was learned from animal models that which of the following areas of the brain is central to the fear response?

A. Amygdala

B. Cortex

C. Cerebellum

D. Medulla oblongata


5. People with post-traumatic stress disorder do not respond to safety signals in the same way as healthy controls.

A. True

B. False


6. Selective serotonin reuptake inhibitors are useful for short-term relief of anxiety disorders and benzodiazepines are the mainstay of long-term pharmacological treatments for the disorder.

A. True

B. False


7. D-cycloserine is a compound that indirectly activates which of the following, known to play a role in fear learning and fear extinction?

A. GAT-1

B. NMDA receptors

C. GABA receptors

D. None of the above


8. The first observation in the placebo controlled study is that D-cycloserine decreased anxiety by itself, indicating that it is an anxiolytic.

A. True

B. False


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