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Immunization, Vaccine Storage, Handling and Safety

General Recommendations on Immunization

1. The timing and spacing of vaccine doses are two of the most important issues in the appropriate use of vaccines.

A. True

B. False


2. Live attenuated vaccines are generally not affected by circulating antibody to the antigen.

A. True

B. False


3. If the live vaccine is given first, it is necessary to wait at least _____ before giving the antibody.

A. 2 weeks

B. 4 weeks

C. 2 months

D. 3 months


4. Because of the importance of rubella and varicella immunity among childbearing age women, women without evidence of immunity to rubella or varicella should receive MMRV vaccine in the postpartum period.

A. True

B. False


5. Individual vaccines should not be mixed in the same syringe unless they are licensed for mixing by the Food and Drug Administration.

A. True

B. False


6. If two live parenteral vaccines or LAIV are administered at an interval of less than 4 weeks, then confirmation of vaccine effectiveness by serologic testing should be performed for the second vaccine given except when given following which vaccine?

A. LAIV

B. Varicella

C. Zoster

D. All of the above


7. Increasing the interval between doses of a multidose vaccine diminishes the effectiveness of the vaccine.

A. True

B. False


8. Vaccine doses administered up to _____ before the minimum interval or age can be counted as valid.

A. 4 months

B. 4 weeks

C. 4 days

D. None of the above


9. Conditions considered permanent precautions to further doses of pediatric DTaP are all of the following, except:

A. Temperatures of 102 degrees Fahrenheit or higher within 48 hours of a dose.

B. Collapse or shock-like state within 48 hours of a dose.

C. Persistent inconsolable crying lasting 3 or more hours occurring within 48 hours of a dose.

D. A seizure, with or without fever, occurring within 3 days of a dose.


10. Anaphylactic reactions are those that:

A. Are mediated by IgE.

B. Occur within minutes or hours of receiving the vaccine.

C. Require medical attention.

D. All of the above.


11. Live vaccines should not be administered to women known to be pregnant.

A. True

B. False


12. Low-grade fever is a contraindication to immunization.

A. True

B. False


13. Antiviral drugs active against herpesviruses (acyclovir, famciclovir) should be discontinued _____ before administration of a varicella-containing vaccine, if possible.

A. 24 hours

B. 48 hours

C. 72 hours

D. 96 hours


14. Vaccination should be withheld if a person is taking antibiotics.

A. True

B. False


Storage and Handling

15. It is better to not vaccinate than to administer a dose of vaccine that has been mishandled.

A. True

B. False


16. Which of the following is a way vaccines may be potentially compromised?

A. Power outages

B. Forgotten vials of vaccine left out on the counter

C. Doses of vaccine stored at improper temperatures

D. All of the above


17. Which of the following personnel should be familiar with the storage and handling policies and procedures for their facility?

A. Those who administer vaccines.

B. Anyone who delivers or accepts vaccine shipments.

C. Anyone who has access to the unit(s) where vaccines are stored.

D. All of the above.


18. As long as it is only temporary, CDC recommends storage of vaccines in a dormitory-style or bar-style, combined refrigerator/freezer unit.

A. True

B. False


19. The desired average refrigerator vaccine storage temperature is:

A. 8 degrees Celsius

B. 5 degrees Celsius

C. 4 degrees Celsius

D. 2 degrees Celsius


Vaccination Safety

20. Healthcare providers are required to report certain adverse health events following specific vaccinations to VAERS and are encouraged to report any clinically significant adverse event after vaccination even if the reporter is not certain that the incident is vaccine-related.

A. True

B. False


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