Malabsorption of food
Altered metabolism
Food and drug interactions
Androgen deficiency
No cooking facilities
Limited income
Reliance on community food programs
With the onset of malnutrition, the client loses weight and experiences several body composition
changes. Starvation results in loss of body fat and muscle. Wasting syndrome produces a loss of
a serious percentage of body weight, with accompanying diarrhea and fever, and has been
considered a defining symptom of AIDS since 1987. The degree of loss of lean body mass can
indicate the length of time that the client has left to live.
Lipodystrophy syndrome
Lipodystrophy syndrome occurs in early end-stage AIDS and produces altered body composition
and various hormonal and physiological changes. The cause of the syndrome and its relationship
with HIV and protease inhibitors are unknown. Because of the disfiguring nature of some
symptoms, lipodystrophy can be particularly distressing for women. Symptoms include
Redistribution of body fat
Increase in waist size
Thinning of the arms and legs
Increased facial wrinkling
Weakness and muscle wasting
Gastrointestinal symptoms
Increased triglycerides and cholesterol
Decreased testosterone levels
Hypertension
Diabetes
To determine body composition changes, provider staff should recommend that clients be
measured on a bioelectrical impedance analysis machine. This noninvasive machine sends a
weak electrical current through electrodes placed on the client's hands and feet to measure fluid
volume, blood cell mass, extracellular mass, and level of body fat. Repeated every 3 to 6 months,
this procedure can provide an accurate gauge of the client's biophysiological status.
Providers can treat weight loss and malnutrition by prescribing a nutritious, balanced diet with
plenty of fluids and a daily multivitamin, if needed. Protein and calorie supplements are
recommended if the client is losing weight. The client should avoid toxic substances such as
alcohol, tobacco, and recreational drugs and should practice a daily routine of moderate exercise.
Pharmaceutical interventions that may be required include appetite stimulants, thalidomide, and
growth hormones.
Treatment staff should also discuss integrative therapies with the client. These can include herbs,